Koronavirusga qarshi dori topildi

Xalqaro tadqiqotchilar guruhi fenofibrat va uning faol shakli fenofibrik kislota inson hujayralaridagi SARS-CoV-2 koronavirusini yoʻq qilishi mumkinligini aniqladi. Bu haqda Frontiers in Pharmacology jurnalida chop etilgan maqolada aytilgan.

Fenofibrat – yurak-qon tomir kasalliklari xavfi boʻlgan bemorlarda xolesterin darajasini pasaytirish uchun ishlatiladigan dori. Olimlar koronavirus boshoqli oqsilining ACE2 uyali retseptorlari bilan bogʻlanish qobiliyatini buzadigan dori izlab, bunga eʼtibor qaratdilar.
Laboratoriya tajribalari shuni koʻrsatdiki, fenofibrat virusni 70 %ga oʻldiradi. Biroq, u SARS-CoV-2 ning koʻplab shtammlariga nisbatan bir xil samaradorlikni koʻrsatdi. Ammo uning koronavirusning «delta» shtammiga qarshi samaradorligi hali oʻrganilmoqda.

Olimlarning taʼkidlashicha, fenofibrat juda arzon va butun dunyoda mavjud, shuning uchun past va oʻrta daromadli mamlakatlarda, shuningdek emlash tavsiya etilmagan bemorlar uchun bu juda foydali boʻlishi mumkin.

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